Allergies & Immunology
Low Dose Immunotherapy and Low Dose Naltrexone for autoimmune disease, chronic inflammation, food and environmental allergies, fibromyalgia, and related conditions. Treatments that address immune dysfunction without suppressing it.
1,500+
Patients Treated
25+
Years Clinical Experience
LDI + LDN
Immune-Modulating Therapies
BL
Brian Lamkin, DO
Founder & Medical Director, The Lamkin Clinic · Board-Certified Physician · 25+ Years Clinical Experience
At The Lamkin Clinic in Edmond, Oklahoma, we treat allergies, autoimmune disease, and chronic inflammatory conditions using two immune-modulating therapies that address the underlying dysfunction rather than suppressing the immune system: Low Dose Immunotherapy (LDI) and Low Dose Naltrexone (LDN).
Autoimmune disease, fibromyalgia, and chronic inflammatory conditions are among the most frustrating diagnoses in modern medicine, not because they are untreatable, but because conventional medicine rarely investigates their underlying cause. Most patients cycle through specialists, receive diagnoses that describe their symptoms rather than explain them, and are offered immune suppression as the primary treatment strategy. At The Lamkin Clinic, we take a different approach. Both LDI and LDN work with the immune system rather than against it, and for many patients in Edmond, Oklahoma City, and the surrounding area, the results have been life-changing.
Treatment Approaches
Low Dose Naltrexone (LDN)
Naltrexone at very low doses (typically 1.5 to 4.5mg) produces a transient opioid receptor blockade that triggers a rebound upregulation of the body's own endorphin production and modulates immune function, particularly microglial activity in the central nervous system.
LDN does not suppress the immune system. It recalibrates it. Clinical evidence and patient outcomes support its use across a wide range of autoimmune, inflammatory, and pain conditions. It is low cost, exceedingly safe, and non-addictive.
Low Dose Immunotherapy (LDI)
Low Dose Immunotherapy uses extremely dilute antigen preparations to retrain the immune system's response to specific triggers including foods, environmental allergens, Candida, and infection-related antigens. Unlike conventional allergy shots, LDI targets immune regulation at the T-regulatory cell level to reduce overall reactivity.
LDI is particularly useful for patients with multiple chemical sensitivities, food reactivity, mast cell activation patterns, and autoimmune conditions with identifiable antigenic triggers.
Conditions Treated with LDI and LDN
- Seasonal and perennial allergies
- Asthma
- Rheumatoid arthritis
- Ankylosing spondylitis
- Systemic lupus erythematosus (SLE)
- Fibromyalgia
- Migraines
- Interstitial cystitis
- Eczema and psoriasis
- Endometriosis
- Hashimoto's thyroiditis
- Multiple sclerosis
- Crohn's disease and IBD
- Chronic pain syndromes
What to Expect from Your Consultation
Dr. Lamkin schedules approximately 45 minutes for your initial consultation. He reviews your complete medical history, current symptoms, prior diagnoses, and relevant lab results. Based on this evaluation, Dr. Lamkin will make treatment recommendations and may order specialty lab testing or in-office diagnostics to better characterize your immune and inflammatory status before beginning therapy.
Monitoring and Follow-Up Protocol
Following your initial consultation, Dr. Lamkin schedules either phone or in-office follow-up monthly for the first three months, then semi-annually. Baseline labs are repeated quarterly for the first year and semi-annually thereafter to monitor response and adjust therapy. This structured follow-up ensures that treatment is working as intended and that any needed modifications are made promptly.
Frequently Asked Questions
What is Low Dose Naltrexone and what conditions does it treat?
Low Dose Naltrexone (LDN) is naltrexone taken at a very low dose, typically 1.5 to 4.5mg, that modulates immune function rather than suppressing it. At The Lamkin Clinic in Edmond, Oklahoma, Dr. Lamkin uses LDN to treat autoimmune conditions including Hashimoto's thyroiditis, rheumatoid arthritis, lupus, fibromyalgia, multiple sclerosis, Crohn's disease, and chronic inflammatory pain syndromes.
What is Low Dose Immunotherapy (LDI) and how does it work?
LDI uses extremely dilute antigen preparations to retrain the immune system's response to specific triggers including foods, environmental allergens, and infection-related antigens. Unlike conventional allergy shots, LDI works at the immune regulatory level to reduce reactivity without suppressing overall immune function. It is particularly useful for patients with multiple chemical sensitivities, food reactivity, and autoimmune conditions with identifiable triggers.
Are LDN and LDI safe treatments?
Both LDN and LDI have excellent safety profiles. LDN does not suppress the immune system, does not cause significant side effects at therapeutic doses in most patients, and is not addictive. It is a low-cost prescription medication. LDI uses antigen preparations at extremely dilute concentrations that are well tolerated. Dr. Lamkin reviews each patient's full history before prescribing and monitors response at regular intervals.
Related Services
Biotoxin Illness & CIRSMold and biotoxin-driven immune dysfunction
Specialty Lab ServicesImmune and autoimmune panel testing
Thyroid OptimizationHashimoto's and autoimmune thyroid disease
Nutrition ServicesFood reactivity and immune nutrition
Functional MedicineRoot-cause investigation for every case
Diagnostic ServicesComprehensive in-clinic testing
Immune Modulation Without Immune Suppression
If you have been living with autoimmune disease, chronic allergies, fibromyalgia, or inflammatory pain and conventional medicine has not provided answers, schedule a consultation at The Lamkin Clinic in Edmond, Oklahoma.
Call us at (405) 285-4762 or request an appointment online.